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Cat. No. Product Name Target Signaling Pathways
T0365 Thioridazine hydrochloride

盐酸硫利达嗪,Mellaril,Aldazine

Apoptosis; Potassium Channel; Dopamine Receptor; 5-HT Receptor; Antibacterial; Adrenergic Receptor; Autophagy Apoptosis; Autophagy; GPCR/G Protein; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
Thioridazine hydrochloride (Mellaril) 是一种多巴胺受体D2家族蛋白的拮抗剂,有抗精神病和抗焦虑活性。它也是一种PI3K-Akt-mTOR 信号通路的抑制剂,具有抗血管生成作用。它在多种类型的癌细胞中显示出抗增殖和凋亡诱导作用,对靶向癌症干细胞具有特异性。
T61476 Thioridazine

Thioridazine is a chemical compound characterized by its potent anti-psychotic and anti-anxiety activities. As an antagonist of the dopamine receptor D2 family proteins, it exhibits a strong inhibitory effect on the PI3K-Akt-mTOR signaling pathways, resulting in anti-angiogenic effects. It also demonstrates significant antiproliferative and apoptosis induction effects in a diverse range of cancer cells, specifically targeting cancer stem cells (CSCs) [1] [2] [3] [4].

化合物

Thioridazine hydrochloride
Cat.No: T0365
Synonym: 盐酸硫利达嗪,Mellaril,Aldazine
Target: Apoptosis, Potassium Channel, Dopamine Receptor, 5-HT Receptor, Antibacterial, Adrenergic Receptor, Autophagy
Thioridazine
Cat.No: T61476
Synonym:
Target:
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